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Primesep HPLC Columns

What are Primesep HPLC Columns?


For decades, liquid chromatography stationary phase design has been dominated by the idea of elimination of multiple, or “unwanted”, interactions that occur in mixed-mode separations. Reverse-phase chromatography is making the point of eliminating silanol interactions with amine-containing analytes by developing base-deactivated phases.

Primesep stationary phases offer unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. A wide range of HPLC columns with id’s from 0.5 mm to 22 mm is available. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service is available for customers. Ask about special custom LC-phases tailored for specific separations.

Primesep HPLC Column Product Range



Primesep Literature for download

Primesep® Columns, Methods, Applications
Primesep® Separation of Ions, New Alternative to Ion Chromatography
Primesep® Solving Problems of Pharmaceutical HPLC Analysiq